Cooperation of two ADAMTS metalloproteases in closure of the mouse palate identifies a requirement for versican proteolysis in regulating palatal mesenchyme proliferation

We have identified a role for two evolutionarily related, secreted metalloproteases of the ADAMTS family, ADAMTS20 and ADAMTS9, in palatogenesis. Adamts20 mutations cause the mouse white-spotting mutant belted (bt), whereas Adamts9 is essential for survival beyond 7.5 days gestation (E7.5). Function...

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Detaylı Bibliyografya
Asıl Yazarlar: Enomoto, Hiroyuki, Nelson, Courtney M., Somerville, Robert P. T., Mielke, Katrina, Dixon, Laura J., Powell, Kimerly, Apte, Suneel S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Company of Biologists 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976286/
https://ncbi.nlm.nih.gov/pubmed/21041365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.050591
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