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Mutational Analysis of Flucytosine Resistance in Candida glabrata
The antifungal flucytosine (5-fluorocytosine [5FC]) is a prodrug metabolized to its toxic form, 5-fluorouracil (5FU), only by organisms expressing cytosine deaminase. One such organism is Candida glabrata, which has emerged as the second most common agent of bloodstream and mucosal candidiasis. This...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology (ASM)
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976130/ https://ncbi.nlm.nih.gov/pubmed/20823283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00605-10 |
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