Acquired Flucytosine Resistance during Combination Therapy with Caspofungin and Flucytosine for Candida glabrata Cystitis

Treatment of Candida glabrata cystitis remains a therapeutic challenge, and an antifungal combination using flucytosine is one option. We describe two patients with refractory C. glabrata cystitis who failed flucytosine combined with caspofungin with early-acquired high-level resistance to flucytosi...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Charlier, Caroline, El Sissy, Carine, Bachelier-Bassi, Sophie, Scemla, Anne, Quesne, Gilles, Sitterlé, Emilie, Legendre, Christophe, Lortholary, Olivier, Bougnoux, Marie-Elisabeth
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704181/
https://ncbi.nlm.nih.gov/pubmed/26525799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02265-15
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