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Should Moxifloxacin Be Used for the Treatment of Extensively Drug-Resistant Tuberculosis? An Answer from a Murine Model

The prevalence of extensively drug-resistant tuberculosis (XDR-TB), defined as TB that is resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. The extent of Mycobacterium tuberculosis resistance to fluoroquinolones depends on the mutation in the DNA gyrase, t...

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書誌詳細
主要な著者: Poissy, Julien, Aubry, Alexandra, Fernandez, Christine, Lott, Marie-Catherine, Chauffour, Aurelie, Jarlier, Vincent, Farinotti, Robert, Veziris, Nicolas
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976119/
https://ncbi.nlm.nih.gov/pubmed/20805388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00968-10
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