Should Moxifloxacin Be Used for the Treatment of Extensively Drug-Resistant Tuberculosis? An Answer from a Murine Model

The prevalence of extensively drug-resistant tuberculosis (XDR-TB), defined as TB that is resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. The extent of Mycobacterium tuberculosis resistance to fluoroquinolones depends on the mutation in the DNA gyrase, t...

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Bibliografiska uppgifter
Huvudupphovsmän: Poissy, Julien, Aubry, Alexandra, Fernandez, Christine, Lott, Marie-Catherine, Chauffour, Aurelie, Jarlier, Vincent, Farinotti, Robert, Veziris, Nicolas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976119/
https://ncbi.nlm.nih.gov/pubmed/20805388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00968-10
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