Should Moxifloxacin Be Used for the Treatment of Extensively Drug-Resistant Tuberculosis? An Answer from a Murine Model

The prevalence of extensively drug-resistant tuberculosis (XDR-TB), defined as TB that is resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. The extent of Mycobacterium tuberculosis resistance to fluoroquinolones depends on the mutation in the DNA gyrase, t...

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Autors principals: Poissy, Julien, Aubry, Alexandra, Fernandez, Christine, Lott, Marie-Catherine, Chauffour, Aurelie, Jarlier, Vincent, Farinotti, Robert, Veziris, Nicolas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976119/
https://ncbi.nlm.nih.gov/pubmed/20805388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00968-10
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