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Should Moxifloxacin Be Used for the Treatment of Extensively Drug-Resistant Tuberculosis? An Answer from a Murine Model

The prevalence of extensively drug-resistant tuberculosis (XDR-TB), defined as TB that is resistant to isoniazid, rifampin, fluoroquinolones, and aminoglycosides, is rising worldwide. The extent of Mycobacterium tuberculosis resistance to fluoroquinolones depends on the mutation in the DNA gyrase, t...

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Detalhes bibliográficos
Main Authors: Poissy, Julien, Aubry, Alexandra, Fernandez, Christine, Lott, Marie-Catherine, Chauffour, Aurelie, Jarlier, Vincent, Farinotti, Robert, Veziris, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976119/
https://ncbi.nlm.nih.gov/pubmed/20805388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00968-10
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