Adult Bone Marrow Stromal Cell-Based Tissue-Engineered Aggrecan Exhibits Ultrastructure and Nanomechanical Properties Superior to Native Cartilage

OBJECTIVE: To quantify the structural characteristics and nanomechanical properties of aggrecan produced by adult bone marrow stromal cells (BMSCs) in peptide hydrogel scaffolds and compare to aggrecan from adult articular cartilage. DESIGN: Adult equine BMSCs were encapsulated in 3D-peptide hydroge...

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Autors principals: Lee, H.-Y., Kopesky, P. W., Plaas, A., Sandy, J., Kisiday, J., Frisbie, D., Grodzinsky, A. J., Ortiz, C.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975943/
https://ncbi.nlm.nih.gov/pubmed/20692354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2010.07.015
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