Controlled Delivery of Transforming Growth Factor β1 by Self-Assembling Peptide Hydrogels Induces Chondrogenesis of Bone Marrow Stromal Cells and Modulates Smad2/3 Signaling

Self-assembling peptide hydrogels were modified to deliver transforming growth factor β1 (TGF-β1) to encapsulated bone-marrow-derived stromal cells (BMSCs) for cartilage tissue engineering applications using two different approaches: (i) biotin-streptavidin tethering; (ii) adsorption to the peptide...

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Detalhes bibliográficos
Main Authors: Kopesky, Paul W., Vanderploeg, Eric J., Kisiday, John D., Frisbie, David D., Sandy, John D., Grodzinsky, Alan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011906/
https://ncbi.nlm.nih.gov/pubmed/20672992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tea.2010.0198
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