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Age-Related Nanostructural and Nanomechanical Changes of Individual Human Cartilage Aggrecan Monomers and Their Glycosaminoglycan Side Chains

The nanostructure and nanomechanical properties of aggrecan monomers extracted and purified from human articular cartilage from donors of different ages (newborn, 29 and 38 year old) were directly visualized and quantified via atomic force microscopy(AFM)-based imaging and force spectroscopy. AFM im...

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Detalhes bibliográficos
Principais autores: Lee, Hsu-Yi, Han, Lin, Roughley, Peter, Grodzinsky, Alan J., Ortiz, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578138/
https://ncbi.nlm.nih.gov/pubmed/23270863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.12.008
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