Age-Related Nanostructural and Nanomechanical Changes of Individual Human Cartilage Aggrecan Monomers and Their Glycosaminoglycan Side Chains

The nanostructure and nanomechanical properties of aggrecan monomers extracted and purified from human articular cartilage from donors of different ages (newborn, 29 and 38 year old) were directly visualized and quantified via atomic force microscopy(AFM)-based imaging and force spectroscopy. AFM im...

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Bibliographic Details
Main Authors: Lee, Hsu-Yi, Han, Lin, Roughley, Peter, Grodzinsky, Alan J., Ortiz, Christine
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578138/
https://ncbi.nlm.nih.gov/pubmed/23270863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.12.008
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