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Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression
Although the PR-Set7/Set8/KMT5a histone H4 Lys 20 monomethyltransferase (H4K20me1) plays an essential role in mammalian cell cycle progression, especially during G2/M, it remained unknown how PR-Set7 itself was regulated. In this study, we discovered the mechanisms that govern the dynamic regulation...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975929/ https://ncbi.nlm.nih.gov/pubmed/20966048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1984210 |
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