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Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression

Although the PR-Set7/Set8/KMT5a histone H4 Lys 20 monomethyltransferase (H4K20me1) plays an essential role in mammalian cell cycle progression, especially during G2/M, it remained unknown how PR-Set7 itself was regulated. In this study, we discovered the mechanisms that govern the dynamic regulation...

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Detalhes bibliográficos
Main Authors: Wu, Shumin, Wang, Weiping, Kong, Xiangduo, Congdon, Lauren M., Yokomori, Kyoko, Kirschner, Marc W., Rice, Judd C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975929/
https://ncbi.nlm.nih.gov/pubmed/20966048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1984210
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