Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila

Combining RNAi in cultured cells and analysis of mutant animals, we probed the roles of known Piwi-interacting RNA (piRNA) pathway components in the initiation and effector phases of transposon silencing. Squash associated physically with Piwi, and reductions in its expression led to modest transpos...

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Bibliografiske detaljer
Main Authors: Haase, Astrid D., Fenoglio, Silvia, Muerdter, Felix, Guzzardo, Paloma M., Czech, Benjamin, Pappin, Darryl J., Chen, Caifu, Gordon, Assaf, Hannon, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2010
Fag:
Research Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975926/
https://ncbi.nlm.nih.gov/pubmed/20966049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1968110
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