Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway

Germline genes often become re-expressed in soma-derived human cancers as “cancer/testis antigens” (CTAs), and piRNA (PIWI-interacting RNA) pathway proteins are found among CTAs. However, whether and how the piRNA pathway contributes to oncogenesis in human neoplasms remain poorly understood. We fou...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Fagegaltier, Delphine, Falciatori, Ilaria, Czech, Benjamin, Castel, Stephane, Perrimon, Norbert, Simcox, Amanda, Hannon, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973292/
https://ncbi.nlm.nih.gov/pubmed/27474441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.284927.116
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