Comt1 Genotype and Expression Predicts Anxiety and Nociceptive Sensitivity in Inbred Strains of Mice

Catechol-O-methyltransferase (COMT) is an ubiquitously expressed enzyme that maintains basic biologic functions by inactivating catechol substrates. In humans, polymorphic variance at the COMT locus has been associated with modulation of pain sensitivity (Andersen & Skorpen, 2009) and risk for d...

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Detalhes bibliográficos
Main Authors: Segall, SK, Nackley, AG, Diatchenko, L, Lariviere, WR, Lu, X, Marron, JS, Grabowski-Boase, L, Walker, JR, Slade, G, Gauthier, J, Bailey, JS, Steffy, BM, Maynard, TM, Tarantino, LM, Wiltshire, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975805/
https://ncbi.nlm.nih.gov/pubmed/20659173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2010.00633.x
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