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Janus Molecule I: Dichotomous Effects of COMT in Neuropathic vs Nociceptive Pain Modalities

The enzyme catechol-O-methyltransferase (COMT) has been shown to play a critical role in pain perception by regulating levels of epinephrine (Epi) and norepinephrine (NE). Although the key contribution of catecholamines to the perception of pain has been recognized for a long time, there is a clear...

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Detalhes bibliográficos
Main Authors: Segall, S.K., Maixner, W., Belfer, I., Wiltshire, T., Seltzer, Z., Diatchenko, L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698056/
https://ncbi.nlm.nih.gov/pubmed/22483297
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