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The Molecular Pathogenesis of Hereditary Ovarian Carcinoma: Alterations in the Tubal Epithelium of Women with BRCA1 and BRCA2 Mutations
BACKGROUND: BRCA1 or BRCA2 (BRCA1/2) mutated ovarian carcinomas may originate in the fallopian tube. We investigated alterations in BRCA1/2 tubal epithelium to define the molecular pathogenesis of these carcinomas. METHODS: Tubal epithelium was evaluated from 31 BRCA1/2 mutation carriers with gyneco...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975783/ https://ncbi.nlm.nih.gov/pubmed/20665887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25439 |
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