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Genomic structure of chromosome 17 deletions in BRCA1 associated ovarian cancers

The aim of this study was to determine the genomic structure of the deletions on chromosome 17 in ovarian carcinomas from women with inherited BRCA1 mutations. Normal and tumor DNA from 14 ovarian tumors associated with inherited BRCA1 mutations were extracted and tested for loss of heterozygosity (...

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Autori principali: Chisholm, Karen M., Goff, Barbara A., Garcia, Rochelle, King, Mary-Claire, Swisher, Elizabeth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2413294/
https://ncbi.nlm.nih.gov/pubmed/18474296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergencyto.2008.02.00
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