Selective displacement of nuclear proteins by antitumor drugs having affinity for nucleic acids.
The nuclear chromatin binding sites of the antitumor drugs mitoxantrone, ametantrone, doxorubicin, mithramycin, and actinomycin D and the intercalating ligand ethidium were studied by polyacrylamide gel electrophoresis of the proteins released from rat liver nuclei in the presence and absence of the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2525781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5151 |
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