High-content assays for evaluating cellular and hepatic diacylglycerol acyltransferase activity

Acyl-CoA:diacylglycerol acyltransferase (DGAT) catalyzes the terminal step in triglyceride (TG) synthesis using diacylglycerol (DAG) and fatty acyl-CoA as substrates. In the liver, the production of VLDL permits the delivery of hydrophobic TG from the liver to peripheral tissues for energy metabolis...

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Bibliographic Details
Main Authors: Qi, Jenson, Lang, Wensheng, Giardino, Edward, Caldwell, Gary W., Smith, Charles, Minor, Lisa K., Darrow, Andrew L., Willemsens, Gustaaf, DeWaepenaert, Katharina, Roevens, Peter, Linders, Joannes T. M., Liang, Yin, Connelly, Margery A.
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2010
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Methods
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975729/
https://ncbi.nlm.nih.gov/pubmed/20805092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D008029
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