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Improved Detection of Rare Genetic Variants for Diseases
Technology advances have promoted gene-based sequencing studies with the aim of identifying rare mutations responsible for complex diseases. A complication in these types of association studies is that the vast majority of non-synonymous mutations are believed to be neutral to phenotypes. It is thus...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975623/ https://ncbi.nlm.nih.gov/pubmed/21079782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013857 |
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