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Analyses and Comparison of Accuracy of Different Genotype Imputation Methods

The power of genetic association analyses is often compromised by missing genotypic data which contributes to lack of significant findings, e.g., in in silico replication studies. One solution is to impute untyped SNPs from typed flanking markers, based on known linkage disequilibrium (LD) relations...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pei, Yu-Fang, Li, Jian, Zhang, Lei, Papasian, Christopher J., Deng, Hong-Wen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569208/
https://ncbi.nlm.nih.gov/pubmed/18958166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003551
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