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Analyses and Comparison of Accuracy of Different Genotype Imputation Methods

The power of genetic association analyses is often compromised by missing genotypic data which contributes to lack of significant findings, e.g., in in silico replication studies. One solution is to impute untyped SNPs from typed flanking markers, based on known linkage disequilibrium (LD) relations...

詳細記述

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書誌詳細
主要な著者: Pei, Yu-Fang, Li, Jian, Zhang, Lei, Papasian, Christopher J., Deng, Hong-Wen
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569208/
https://ncbi.nlm.nih.gov/pubmed/18958166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003551
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