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Analyses and Comparison of Accuracy of Different Genotype Imputation Methods

The power of genetic association analyses is often compromised by missing genotypic data which contributes to lack of significant findings, e.g., in in silico replication studies. One solution is to impute untyped SNPs from typed flanking markers, based on known linkage disequilibrium (LD) relations...

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Bibliographic Details
Main Authors: Pei, Yu-Fang, Li, Jian, Zhang, Lei, Papasian, Christopher J., Deng, Hong-Wen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569208/
https://ncbi.nlm.nih.gov/pubmed/18958166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003551
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