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A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.

We have determined that Salmonella typhimurium strains with mutations in the positive regulatory locus phoP are markedly attenuated in virulence for BALB/c mice. The DNA sequence for the phoP locus indicates that it is composed of two genes present in an operon, termed phoP and phoQ. The deduced ami...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Miller, S I, Kukral, A M, Mekalanos, J J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297555/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544889/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5054
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