A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.

We have determined that Salmonella typhimurium strains with mutations in the positive regulatory locus phoP are markedly attenuated in virulence for BALB/c mice. The DNA sequence for the phoP locus indicates that it is composed of two genes present in an operon, termed phoP and phoQ. The deduced ami...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Miller, S I, Kukral, A M, Mekalanos, J J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5054
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