A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence.

We have determined that Salmonella typhimurium strains with mutations in the positive regulatory locus phoP are markedly attenuated in virulence for BALB/c mice. The DNA sequence for the phoP locus indicates that it is composed of two genes present in an operon, termed phoP and phoQ. The deduced ami...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Miller, S I, Kukral, A M, Mekalanos, J J
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297555/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544889/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5054
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