Nuclear Retention of Unspliced Pre-mRNAs by Mutant DHX16/hPRP2, a Spliceosomal DEAH-box Protein

Defective or imbalanced expression of spliceosomal factors has been linked to human disease; however, how a defective spliceosome affects intron-containing gene transcripts in human cells is largely unknown. DEAH-box protein DHX16 is a human orthologue of Saccharomyces cerevisiae spliceosomal protei...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Gencheva, Marieta, Lin, Ting-Yu, Wu, Xiwei, Yang, Lixin, Richard, Caroline, Jones, Matthew, Lin, Shwu-Bin, Lin, Ren-Jang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
RNA
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975187/
https://ncbi.nlm.nih.gov/pubmed/20841358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.122309
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky