Sustained Glutamate Receptor Activation Down-regulates GABA(B) Receptors by Shifting the Balance from Recycling to Lysosomal Degradation

Metabotropic GABA(B) receptors are abundantly expressed at glutamatergic synapses where they control excitability of the synapse. Here, we tested the hypothesis that glutamatergic neurotransmission may regulate GABA(B) receptors. We found that application of glutamate to cultured cortical neurons le...

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Detalles Bibliográficos
Main Authors: Maier, Patrick J., Marin, Isabel, Grampp, Thomas, Sommer, Andrea, Benke, Dietmar
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Neurobiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975185/
https://ncbi.nlm.nih.gov/pubmed/20826795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142406
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