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N-terminal Domain of Myelin Basic Protein Inhibits Amyloid β-Protein Fibril Assembly
Accumulation of amyloid β-protein (Aβ) into brain parenchymal plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related disorders. Aβ peptides readily form β-sheet-containing oligomers and fibrils. Previously, we reported a strong interaction between myelin basi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975183/ https://ncbi.nlm.nih.gov/pubmed/20807757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169599 |
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