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Dasatinib blocks cetuximab- and radiation-induced nuclear translocation of the epidermal growth factor receptor in head and neck squamous cell carcinoma

BACKGROUND AND PURPOSE: The aberrant expression of epidermal growth factor receptor (EGFR) has been linked to the etiology of head and neck squamous cell carcinoma (HNSCC). The first major phase III trial combining cetuximab with radiation confirmed a strong survival advantage. However, both cetuxim...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Chunrong, Iida, Mari, Dunn, Emily F., Wheeler, Deric L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974772/
https://ncbi.nlm.nih.gov/pubmed/20667610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2010.06.010
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