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Comparison of the Replication and Persistence of Simian-Human Immunodeficiency Viruses Expressing Vif Proteins with Mutation of the SLQYLA or HCCH Domains in Macaques
The Vif protein of primate lentiviruses interacts with APOBEC3 proteins, which results in shunting of the APOBEC3-Vif complex to the proteosome for degradation. Using the simian-human immunodeficiency virus (SHIV)/macaque model, we compared the replication and pathogenicity of SHIVs that express a V...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974619/ https://ncbi.nlm.nih.gov/pubmed/20627348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.04.017 |
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