Angiogenic factor signaling regulates centrosome duplication in endothelial cells of developing blood vessels

Regulated vascular endothelial growth factor (VEGF) signaling is required for proper angiogenesis, and excess VEGF signaling results in aberrantly formed vessels that do not function properly. Tumor endothelial cells have excess centrosomes and are aneuploid, properties that probably contribute to t...

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Autors principals: Taylor, Sarah M., Nevis, Kathleen R., Park, Hannah L., Rogers, Gregory C., Rogers, Stephen L., Cook, Jeanette G., Bautch, Victoria L.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Vascular Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974614/
https://ncbi.nlm.nih.gov/pubmed/20664058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-266197
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