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Drug-dependent clearance of human platelets in the NOD/scid mouse by antibodies from patients with drug-induced immune thrombocytopenia

Drug-induced immune thrombocytopenia (DITP) is a relatively common and sometimes life-threatening condition caused by antibodies that bind avidly to platelets only when drug is present. How drug-dependent antibodies (DDAbs) are induced and how drugs promote their interaction with platelets are poorl...

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Detalhes bibliográficos
Main Authors: Bougie, Daniel W., Nayak, Dhirendra, Boylan, Brian, Newman, Peter J., Aster, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974608/
https://ncbi.nlm.nih.gov/pubmed/20587782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-277764
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