Fully modified 2′ MOE oligonucleotides redirect polyadenylation
Many genes have been described and characterized that have alternative polyadenylation signals at the 3′-end of their pre-mRNAs. Many of these same messages also contain destabilization motifs responsible for rapid degradation of the mRNA. Polyadenylation site selection can thus determine the stabil...
Tallennettuna:
| Julkaisussa: | Nucleic Acids Res |
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| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Oxford University Press
2001
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC29745/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238995/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.6.1293 |
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