Phase Separation of Parkinson's Disease Protein α‐Synuclein: Mechanistic Insights but Biological Uncertainties

Assembly of the protein α‐synuclein into ordered cross‐β amyloid fibrils is the key hallmark of Parkinson's disease. The molecular processes involved in the transition of functional α‐synuclein monomers to pathological amyloids remain unclear. Liquid–liquid phase separation has emerged as a possible...

Full description

Bibliographic Details

Main Authors:	Simran Arora, Pernilla Wittung‐Stafshede
Format:	Artigo
Language:	Inglês
Published:	Wiley-VCH 2026-05-01
Series:	ChemistryEurope
Subjects:	α‐synuclein amyloid fibrils biomolecular condensates heterotypic condensates intrinsically disordered proteins liquid–liquid phase separation
Online Access:	https://doi.org/10.1002/ceur.70304
Tags:	Add Tag No Tags, Be the first to tag this record!