Relative Role of Genetic Complement Abnormalities in Sporadic and Familial aHUS and Their Impact on Clinical Phenotype

Background and objectives: Hemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal impairment. Most childhood cases are caused by Shiga toxin–producing bacteria. The other form, atypical HUS (aHUS), accounts for 10% of cases and has a poor p...

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Autori principali: Noris, Marina, Caprioli, Jessica, Bresin, Elena, Mossali, Chiara, Pianetti, Gaia, Gamba, Sara, Daina, Erica, Fenili, Chiara, Castelletti, Federica, Sorosina, Annalisa, Piras, Rossella, Donadelli, Roberta, Maranta, Ramona, van der Meer, Irene, Conway, Edward M., Zipfel, Peter F., Goodship, Timothy H., Remuzzi, Giuseppe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Nephrology 2010
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974386/
https://ncbi.nlm.nih.gov/pubmed/20595690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.02210310
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