Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat—possible involvement of kynurenic acid

PURPOSE: This study investigated the effects of systemically administered lithium acetoacetate (ACA) and sodium β-hydroxybutyrate (BHB) in a rat model of N-methyl-D-aspartate (NMDA)-induced damage of retinal ganglion cells (RGC). Additionally, the influence of ACA and BHB on kynurenic acid (KYNA) pr...

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Hlavní autoři: Thaler, Sebastian, Choragiewicz, Tomasz J., Rejdak, Robert, Fiedorowicz, Michal, Turski, Waldemar A., Tulidowicz-Bielak, Maria, Zrenner, Eberhart, Schuettauf, Frank, Zarnowski, Tomasz
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2010
Témata:
Basic Science
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974203/
https://ncbi.nlm.nih.gov/pubmed/20532550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00417-010-1425-7
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