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A Straightforward Route to Functionalized “trans-Diels–Alder” Motifs

[Image: see text] A sequence consisting of Lewis acid-catalyzed Diels–Alder reaction on a 2-halocyclohexenone, followed by reductive alkylation provides a route to trans-fused octalinones bearing angular methyl groups with functionality corresponding to that which would have been possible from trans...

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Autors principals: Lee, Jun Hee, Zhang, Yandong, Danishefsky, Samuel J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974171/
https://ncbi.nlm.nih.gov/pubmed/20863105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1073855
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