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Parenteral Delivery of HPβCD: Effects on Drug-HSA Binding
It is thought that cyclodextrins, such as 2-hydroxypropyl-β-cyclodextrin (HPβCD), will at high concentration affect pharmacokinetics of drugs through competitive binding with plasma proteins. Albumin is the major component of plasma proteins responsible for plasma protein binding. The purpose of thi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2974121/ https://ncbi.nlm.nih.gov/pubmed/20658211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9482-0 |
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