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Floating Tablet of Trimetazidine Dihydrochloride: An Approach for Extended Release with Zero-Order Kinetics

Trimetazidine dihydrochloride is an effective anti-anginal agent; however, it is freely soluble in water and suffers from a relatively short half-life. To solve this encumbrance, it is a prospective candidate for fabricating trimetazidine extended-release formulations. Trimetazidine extended-release...

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Autores principales: Abdelbary, Ahmed, El-Gazayerly, Omaima N., El-Gendy, Nashwa A., Ali, Adel A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974115/
https://ncbi.nlm.nih.gov/pubmed/20582493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9468-y
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