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Application of Pharmaceutical QbD for Enhancement of the Solubility and Dissolution of a Class II BCS Drug using Polymeric Surfactants and Crystallization Inhibitors: Development of Controlled-Release Tablets

The aim of this study was to apply quality by design (QbD) for pharmaceutical development of felodipine solid mixture (FSM) containing hydrophilic carriers and/or polymeric surfactants, for easier development of controlled-release tablets of felodipine. The material attributes, the process parameter...

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Detalhes bibliográficos
Main Authors: Basalious, Emad B., El-Sebaie, Wessam, El-Gazayerly, Omaima
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167259/
https://ncbi.nlm.nih.gov/pubmed/21701960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-011-9646-6
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