Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration

Purpose: Eye drops’ formulations of poorly water-soluble drugs, offer the advantage of crossing the lipophilic cornea, but their limited aqueous solubility may lead to low ocular bioavailability limiting their therapeutic uses. Terconazole (TZ) is an antifungal drug with low aqueous solubility, rest...

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Detalhes bibliográficos
Main Authors: Carol Yousry, Pakinam Mohsen Zikry, Emad Basalious Basalious, Omaima Naem El-Gazayerly
Formato: Artigo
Idioma:Inglês
Publicado em: Tabriz University of Medical Sciences 2020-05-01
Colecção:Advanced Pharmaceutical Bulletin
Assuntos:
chorioallantoic membrane
high pressure liquid chromatography
oils
surface-active agent
terconazole
transmission electron microscopy
Acesso em linha:https://apb.tbzmed.ac.ir/PDF/apb-28043
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