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Feasibility of optimizing trimetazidine dihydrochloride release from controlled porosity osmotic pump tablets of directly compressed cores

The aim of this study was to develop and optimize Trimetazidine dihydrochloride (TM) controlled porosity osmotic pump (CPOP) tablets of directly compressed cores. A 2(3) full factorial design was used to study the influence of three factors namely: PEG400 (10% and 25% based on coating polymer weight...

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Библиографические подробности
Опубликовано в: :J Adv Res
Главные авторы: Habib, Basant A., Rehim, Randa T. Abd El, Nour, Samia A.
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294720/
https://ncbi.nlm.nih.gov/pubmed/25685502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2013.05.005
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