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Feasibility of optimizing trimetazidine dihydrochloride release from controlled porosity osmotic pump tablets of directly compressed cores

The aim of this study was to develop and optimize Trimetazidine dihydrochloride (TM) controlled porosity osmotic pump (CPOP) tablets of directly compressed cores. A 2(3) full factorial design was used to study the influence of three factors namely: PEG400 (10% and 25% based on coating polymer weight...

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Detalhes bibliográficos
Publicado no:J Adv Res
Main Authors: Habib, Basant A., Rehim, Randa T. Abd El, Nour, Samia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294720/
https://ncbi.nlm.nih.gov/pubmed/25685502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jare.2013.05.005
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