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Homolog of tocopherol C methyltransferases catalyzes N methylation in anticancer alkaloid biosynthesis
Madagascar periwinkle (Catharanthus roseus) is the sole source of the anticancer drugs vinblastine and vincristine, bisindole alkaloids derived from the dimerization of the terpenoid indole alkaloids vindoline and catharanthine. Full elucidation of the biosynthetic pathways of these compounds is a p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2973921/ https://ncbi.nlm.nih.gov/pubmed/20956330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009003107 |
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