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Human-Specific Evolution and Adaptation Led to Major Qualitative Differences in the Variable Receptors of Human and Chimpanzee Natural Killer Cells

Natural killer (NK) cells serve essential functions in immunity and reproduction. Diversifying these functions within individuals and populations are rapidly-evolving interactions between highly polymorphic major histocompatibility complex (MHC) class I ligands and variable NK cell receptors. Specif...

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Detalhes bibliográficos
Main Authors: Abi-Rached, Laurent, Moesta, Achim K., Rajalingam, Raja, Guethlein, Lisbeth A., Parham, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2973822/
https://ncbi.nlm.nih.gov/pubmed/21079681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001192
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