Direct involvement of σ-1 receptors in the dopamine D(1) receptor-mediated effects of cocaine

It is well known that cocaine blocks the dopamine transporter. This mechanism should lead to a general increase in dopaminergic neurotransmission, and yet dopamine D(1) receptors (D(1)Rs) play a more significant role in the behavioral effects of cocaine than the other dopamine receptor subtypes. Coc...

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Dettagli Bibliografici
Autori principali: Navarro, Gemma, Moreno, Estefanía, Aymerich, Marisol, Marcellino, Daniel, McCormick, Peter J., Mallol, Josefa, Cortés, Antoni, Casadó, Vicent, Canela, Enric I., Ortiz, Jordi, Fuxe, Kjell, Lluís, Carmen, Ferré, Sergi, Franco, Rafael
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972946/
https://ncbi.nlm.nih.gov/pubmed/20956312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008911107
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