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Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins
Surface Ig (sIg) of follicular lymphoma (FL) is vital for tumor cell survival. We found previously that the Ig in FL is unusual, because the variable region genes carry sequence motifs for N-glycan addition. These are introduced by somatic mutation and are tumor specific. Unexpectedly, added glycans...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972945/ https://ncbi.nlm.nih.gov/pubmed/20937880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009388107 |
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