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Dual selection mechanisms drive efficient single-gene reverse genetics for rotavirus
Current methods for engineering the segmented double-stranded RNA genome of rotavirus (RV) are limited by inefficient recovery of the recombinant virus. In an effort to expand the utility of RV reverse genetics, we developed a method to recover recombinant viruses in which independent selection stra...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972929/ https://ncbi.nlm.nih.gov/pubmed/20937889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011948107 |
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