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Generation of Genetically Stable Recombinant Rotaviruses Containing Novel Genome Rearrangements and Heterologous Sequences by Reverse Genetics

The rotavirus (RV) genome consists of 11 segments of double-stranded RNA (dsRNA). Typically, each segment contains 5′ and 3′ untranslated regions (UTRs) that flank an open reading frame (ORF) encoding a single protein. RV variants with segments of atypical size owing to sequence rearrangements have...

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書目詳細資料
Main Authors: Navarro, Aitor, Trask, Shane D., Patton, John T.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648102/
https://ncbi.nlm.nih.gov/pubmed/23536662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00413-13
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