Relating the shape of protein binding sites to binding affinity profiles: is there an association?

BACKGROUND: Various pattern-based methods exist that use in vitro or in silico affinity profiles for classification and functional examination of proteins. Nevertheless, the connection between the protein affinity profiles and the structural characteristics of the binding sites is still unclear. Our...

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Main Authors: Simon, Zoltán, Vigh-Smeller, Margit, Peragovics, Ágnes, Csukly, Gábor, Zahoránszky-Kőhalmi, Gergely, Rauscher, Anna Á, Jelinek, Balázs, Hári, Péter, Bitter, István, Málnási-Csizmadia, András, Czobor, Pál
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972294/
https://ncbi.nlm.nih.gov/pubmed/20923553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-10-32
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