Metabolism of α-methyltyrosine in man: relationship to its potency as an inhibitor of catecholamine biosynthesis

The metabolic fate of the tyrosine hydroxylase inhibitor, α-methyl-para-tyrosine (α-MPT), was studied after oral administration of single and multiple doses to patients with pheochromocytoma and essential hypertension. No major urinary excretion product was found other than the drug itself, which ac...

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Podrobná bibliografie

Vydáno v:	J Clin Invest
Hlavní autoři:	Engelman, Karl, Jéquier, Eric, Udenfriend, Sidney, Sjoerdsma, Albert
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 1968
Témata:	Articles
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5637144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105753
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